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M J Owen Selected Research

Apolipoproteins E (ApoE)

12/2013Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
1/2009Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample.
12/2000Susceptibility locus for Alzheimer's disease on chromosome 10.
5/2000APOE epsilon 4 influences the manifestation of Alzheimer's disease in adults with Down's syndrome.

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M J Owen Research Topics

Disease

38Schizophrenia (Dementia Praecox)
01/2018 - 03/2000
20Bipolar Disorder (Manic Depressive Psychosis)
02/2015 - 03/2000
10Psychotic Disorders (Schizoaffective Disorder)
01/2018 - 04/2000
10Alzheimer Disease (Alzheimer's Disease)
12/2013 - 05/2000
7Mental Disorders (Mental Disorder)
02/2015 - 05/2002
6Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
04/2011 - 01/2002
4Intellectual Disability (Idiocy)
07/2015 - 09/2005
4Mood Disorders (Mood Disorder)
01/2005 - 04/2000
3Neutropenia
01/2018 - 10/2017
2Autistic Disorder (Autism)
07/2015 - 02/2012
2Major Depressive Disorder (Major Depressive Disorders)
02/2015 - 09/2008
2Darier Disease (Darier's Disease)
01/2002 - 01/2001
2Cataract (Cataracts)
04/2000 - 02/2000
1Agranulocytosis (Granulocytopenia)
10/2017
1Muscular Diseases (Myopathy)
10/2017
1Drug-Related Side Effects and Adverse Reactions
10/2017
1Autism Spectrum Disorder
02/2015
1Epilepsy (Aura)
02/2012
1AIDS-Related Complex (ARC)
02/2012
1Neurodevelopmental Disorders
04/2011
1Hemochromatosis (Bronze Diabetes)
06/2010
1Depressive Disorder (Melancholia)
09/2008
1Genetic Predisposition to Disease (Genetic Predisposition)
09/2008
1Amyloid Plaque
06/2007
1succinic semialdehyde dehydrogenase deficiency
06/2004
1Learning Disabilities (Learning Disability)
06/2004
1Retinal Detachment (Retinal Detachments)
09/2002

Drug/Important Bio-Agent (IBA)

15Proteins (Proteins, Gene)FDA Link
01/2016 - 05/2000
6Biological ProductsIBA
07/2015 - 09/2005
5Clozapine (Clozaril)FDA LinkGeneric
01/2018 - 01/2004
4Antipsychotic Agents (Antipsychotics)IBA
10/2017 - 03/2000
4Apolipoproteins E (ApoE)IBA
12/2013 - 05/2000
4ApolipoproteinsIBA
12/2013 - 05/2000
4DNA (Deoxyribonucleic Acid)IBA
08/2009 - 01/2002
3N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2016 - 01/2002
3Dopamine (Intropin)FDA LinkGeneric
05/2004 - 09/2000
2GABA-A Receptors (GABA(A) Receptor)IBA
02/2010 - 05/2009
2Neuregulin-1 (Neuregulin 1)IBA
01/2010 - 05/2003
2Transcription Factors (Transcription Factor)IBA
09/2009 - 10/2005
2Carrier Proteins (Binding Protein)IBA
01/2009 - 04/2004
2Messenger RNA (mRNA)IBA
10/2008 - 12/2007
23' Untranslated Regions (3' UTR)IBA
11/2005 - 11/2001
2Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA
11/2005 - 05/2002
2Brain-Derived Neurotrophic Factor (BDNF)IBA
10/2005 - 03/2005
2GTP-Binding Proteins (G-Protein)IBA
09/2005 - 05/2004
2Glutamic Acid (Glutamate)FDA Link
07/2003 - 06/2000
25' Untranslated Regions (5' UTR)IBA
01/2002 - 04/2001
2Dopamine D3 ReceptorsIBA
01/2002 - 05/2001
2CalciumIBA
01/2002 - 01/2001
2Nonsense Codon (Nonsense Mutation)IBA
11/2001 - 09/2001
2Amino AcidsFDA Link
11/2001 - 09/2000
2NeurotensinIBA
09/2000 - 03/2000
2proneurotensinIBA
03/2000 - 03/2000
1Complement C4 (Complement Component 4)IBA
01/2018
1RNA (Ribonucleic Acid)IBA
01/2018
1Simvastatin (Zocor)FDA LinkGeneric
10/2017
1HLA Antigens (Human Leukocyte Antigens)IBA
10/2017
1Docetaxel (Taxotere)FDA Link
10/2017
1NucleotidesIBA
01/2016
1Fragile X Mental Retardation ProteinIBA
01/2016
1Mitochondrial DNA (mtDNA)IBA
04/2012
1Steryl-Sulfatase (Steroid Sulfatase)IBA
04/2011
1Protein Kinase C-alphaIBA
11/2010
1Calcium Channels (Calcium Channel)IBA
10/2010
1Factor X (Stuart Factor)IBA
08/2010
1Transferrin (beta 2 Transferrin)IBA
06/2010
1IronIBA
06/2010
1DysbindinIBA
04/2010
1Synaptosomal-Associated Protein 25IBA
10/2009
1Dynamins (Dynamin)IBA
01/2009
1Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA
01/2009
15-methyltetrahydrofolateIBA
09/2008
1Neurotransmitter Agents (Neurotransmitter)IBA
09/2008
15,10-methylenetetrahydrofolic acidIBA
09/2008
1Oxidoreductases (Dehydrogenase)IBA
09/2008
1Class 5 Receptor-Like Protein Tyrosine PhosphatasesIBA
02/2008
1NeuregulinsIBA
02/2008
1Phencyclidine (Angel Dust)IBA
12/2007
1Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
12/2007
1Amyloid beta-PeptidesIBA
06/2007
1Growth Hormone (Somatotropin)IBA
01/2007
1Insulin-Like Growth Factor I (IGF-1)IBA
01/2007
1Insulin ReceptorIBA
01/2007
1Insulin-Like PeptidesIBA
01/2007
1antineoplaston A10 (A 10)IBA
07/2006
1EnzymesIBA
05/2006
1Cadherins (E-Cadherin)IBA
04/2006
1Valine (L-Valine)FDA Link
10/2005
1D-Amino-Acid Oxidase (D-Amino Acid Dehydrogenase)IBA
09/2005
1Pharmaceutical PreparationsIBA
01/2005
1LithiumIBA
01/2005
1myo-inositol-1 (or 4)-monophosphatase (inositol monophosphatase)IBA
01/2005
1Succinate-Semialdehyde Dehydrogenase (Succinic Semialdehyde Dehydrogenase)IBA
06/2004
1dystrobrevinIBA
04/2004
1Psychotropic Drugs (Psychoactive Drugs)IBA
01/2004
1Homer Scaffolding Proteins (Homer 1)IBA
07/2003
1Proline Oxidase (Proline Dehydrogenase)IBA
07/2003
1Dopa DecarboxylaseIBA
02/2003
1CollagenIBA
09/2002

Therapy/Procedure

1Therapeutics
01/2005